AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas

Patients with inoperable or unresectable pancreatic neuroendocrine tumors (NETs) have limited treatment options. These rare human tumors often express somatostatin receptors (SSTRs) and thus are clinically responsive to certain relatively stable somatostatin analogs, such as octreotide. Unfortunatel...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Smith, Tracey L., Yuan, Ziqiang, Cardó-Vila, Marina, Sanchez Claros, Carmen, Adem, Asha, Cui, Min-Hui, Branch, Craig A., Gelovani, Juri G., Libutti, Steven K., Sidman, Richard L., Pasqualini, Renata, Arap, Wadih
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780640/
https://ncbi.nlm.nih.gov/pubmed/26884209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525709113
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