AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas

Patients with inoperable or unresectable pancreatic neuroendocrine tumors (NETs) have limited treatment options. These rare human tumors often express somatostatin receptors (SSTRs) and thus are clinically responsive to certain relatively stable somatostatin analogs, such as octreotide. Unfortunatel...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Smith, Tracey L., Yuan, Ziqiang, Cardó-Vila, Marina, Sanchez Claros, Carmen, Adem, Asha, Cui, Min-Hui, Branch, Craig A., Gelovani, Juri G., Libutti, Steven K., Sidman, Richard L., Pasqualini, Renata, Arap, Wadih
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780640/
https://ncbi.nlm.nih.gov/pubmed/26884209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525709113
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