AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas

Patients with inoperable or unresectable pancreatic neuroendocrine tumors (NETs) have limited treatment options. These rare human tumors often express somatostatin receptors (SSTRs) and thus are clinically responsive to certain relatively stable somatostatin analogs, such as octreotide. Unfortunatel...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Smith, Tracey L., Yuan, Ziqiang, Cardó-Vila, Marina, Sanchez Claros, Carmen, Adem, Asha, Cui, Min-Hui, Branch, Craig A., Gelovani, Juri G., Libutti, Steven K., Sidman, Richard L., Pasqualini, Renata, Arap, Wadih
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780640/
https://ncbi.nlm.nih.gov/pubmed/26884209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525709113
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