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The light chains of kinesin-1 are autoinhibited

The light chains (KLCs) of the microtubule motor kinesin-1 bind cargoes and regulate its activity. Through their tetratricopeptide repeat domain (KLC(TPR)), they can recognize short linear peptide motifs found in many cargo proteins characterized by a central tryptophan flanked by aspartic/glutamic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Yip, Yan Y., Pernigo, Stefano, Sanger, Anneri, Xu, Mengjia, Parsons, Maddy, Steiner, Roberto A., Dodding, Mark P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780624/
https://ncbi.nlm.nih.gov/pubmed/26884162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520817113
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