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Sialylation of anti‐histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells

The Fc portion of immunoglobulin (Ig)G harbours a single glycosylation site. Glycan sialylation is critical for structure and for certain effector functions of IgG. Anti‐histone IgG of patients with systemic lupus erythematosus is reportedly responsible for the recruitment of polymorphonuclear cells...

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Bibliografski detalji
Izdano u:Clin Exp Immunol
Glavni autori: Magorivska, I., Muñoz, L. E., Janko, C., Dumych, T., Rech, J., Schett, G., Nimmerjahn, F., Bilyy, R., Herrmann, M.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778101/
https://ncbi.nlm.nih.gov/pubmed/26618514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12744
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