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Sialylation of anti‐histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells
The Fc portion of immunoglobulin (Ig)G harbours a single glycosylation site. Glycan sialylation is critical for structure and for certain effector functions of IgG. Anti‐histone IgG of patients with systemic lupus erythematosus is reportedly responsible for the recruitment of polymorphonuclear cells...
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| Publicado no: | Clin Exp Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778101/ https://ncbi.nlm.nih.gov/pubmed/26618514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12744 |
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