The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation

To analyze the glycosylation of anti-β2GP1, we investigated purified IgG from healthy children, patients with APS, and asymptomatic adult carriers of antiphospholipid antibodies. We observed that in the sera of healthy children and of patients with APS, IgG3 and IgG2 were predominant, respectively....

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Fickentscher, Christoph, Magorivska, Iryna, Janko, Christina, Biermann, Mona, Bilyy, Rostyslav, Nalli, Cecilia, Tincani, Angela, Medeghini, Veronica, Meini, Antonella, Nimmerjahn, Falk, Schett, Georg, Muñoz, Luis E., Andreoli, Laura, Herrmann, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491572/
https://ncbi.nlm.nih.gov/pubmed/26185769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/638129
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