The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation

To analyze the glycosylation of anti-β2GP1, we investigated purified IgG from healthy children, patients with APS, and asymptomatic adult carriers of antiphospholipid antibodies. We observed that in the sera of healthy children and of patients with APS, IgG3 and IgG2 were predominant, respectively....

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Vydáno v:J Immunol Res
Hlavní autoři: Fickentscher, Christoph, Magorivska, Iryna, Janko, Christina, Biermann, Mona, Bilyy, Rostyslav, Nalli, Cecilia, Tincani, Angela, Medeghini, Veronica, Meini, Antonella, Nimmerjahn, Falk, Schett, Georg, Muñoz, Luis E., Andreoli, Laura, Herrmann, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491572/
https://ncbi.nlm.nih.gov/pubmed/26185769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/638129
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