The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation

To analyze the glycosylation of anti-β2GP1, we investigated purified IgG from healthy children, patients with APS, and asymptomatic adult carriers of antiphospholipid antibodies. We observed that in the sera of healthy children and of patients with APS, IgG3 and IgG2 were predominant, respectively....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol Res
Egile Nagusiak: Fickentscher, Christoph, Magorivska, Iryna, Janko, Christina, Biermann, Mona, Bilyy, Rostyslav, Nalli, Cecilia, Tincani, Angela, Medeghini, Veronica, Meini, Antonella, Nimmerjahn, Falk, Schett, Georg, Muñoz, Luis E., Andreoli, Laura, Herrmann, Martin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491572/
https://ncbi.nlm.nih.gov/pubmed/26185769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/638129
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