The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation

To analyze the glycosylation of anti-β2GP1, we investigated purified IgG from healthy children, patients with APS, and asymptomatic adult carriers of antiphospholipid antibodies. We observed that in the sera of healthy children and of patients with APS, IgG3 and IgG2 were predominant, respectively....

Full description

Saved in:
Bibliographic Details
Published in:J Immunol Res
Main Authors: Fickentscher, Christoph, Magorivska, Iryna, Janko, Christina, Biermann, Mona, Bilyy, Rostyslav, Nalli, Cecilia, Tincani, Angela, Medeghini, Veronica, Meini, Antonella, Nimmerjahn, Falk, Schett, Georg, Muñoz, Luis E., Andreoli, Laura, Herrmann, Martin
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491572/
https://ncbi.nlm.nih.gov/pubmed/26185769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/638129
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items