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Sialylation of anti‐histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells
The Fc portion of immunoglobulin (Ig)G harbours a single glycosylation site. Glycan sialylation is critical for structure and for certain effector functions of IgG. Anti‐histone IgG of patients with systemic lupus erythematosus is reportedly responsible for the recruitment of polymorphonuclear cells...
Shranjeno v:
| izdano v: | Clin Exp Immunol |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778101/ https://ncbi.nlm.nih.gov/pubmed/26618514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12744 |
| Oznake: |
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