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SREBP2 Activation Induces Hepatic Long-chain Acyl-CoA Synthetase 1 (ACSL1) Expression in Vivo and in Vitro through a Sterol Regulatory Element (SRE) Motif of the ACSL1 C-promoter

Long-chain acyl-CoA synthetase 1 (ACSL1) plays a key role in fatty acid metabolism. To identify novel transcriptional modulators of ACSL1, we examined ACSL1 expression in liver tissues of hamsters fed a normal diet, a high fat diet, or a high cholesterol and high fat diet (HCHFD). Feeding hamsters H...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Singh, Amar Bahadur, Kan, Chin Fung Kelvin, Dong, Bin, Liu, Jingwen
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777867/
https://ncbi.nlm.nih.gov/pubmed/26728456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.696872
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