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Identification of a novel function of hepatic long-chain acyl-CoA synthetase-1 (ACSL1) in bile acid synthesis and its regulation by bile acid-activated farnesoid X receptor
Long-chain acyl-CoA synthetase 1 (ACSL1) plays a pivotal role in fatty acid β-oxidation in heart, adipose tissue and skeletal muscle. However, key functions of ACSL1 in the liver remain largely unknown. We investigated acute effects of hepatic ACSL1 deficiency on lipid metabolism in adult mice under...
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| Publicado no: | Biochim Biophys Acta Mol Cell Biol Lipids |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6604619/ https://ncbi.nlm.nih.gov/pubmed/30580099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.12.012 |
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