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Base and Nucleotide Excision Repair of Oxidatively Generated Guanine Lesions in DNA
The well known biomarker of oxidative stress, 8-oxo-7,8-dihydroguanine, is more susceptible to further oxidation than the parent guanine base and can be oxidatively transformed to the genotoxic spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh) lesions. Incubation of 135-mer duplexes with sing...
Gardado en:
| Publicado en: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777862/ https://ncbi.nlm.nih.gov/pubmed/26733197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693218 |
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