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Structure of the Regulator of G Protein Signaling 8 (RGS8)-Gα(q) Complex: MOLECULAR BASIS FOR Gα SELECTIVITY
Regulator of G protein signaling (RGS) proteins interact with activated Gα subunits via their RGS domains and accelerate the hydrolysis of GTP. Although the R4 subfamily of RGS proteins generally accepts both Gα(i/o) and Gα(q/11) subunits as substrates, the R7 and R12 subfamilies select against Gα(q...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777848/ https://ncbi.nlm.nih.gov/pubmed/26755720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712075 |
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