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Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases
Bacterial l-asparaginases play an important role in the treatment of certain types of blood cancers. We are exploring the guinea pig l-asparaginase (gpASNase1) as a potential replacement of the immunogenic bacterial enzymes. The exact mechanism used by l-asparaginases to catalyze the hydrolysis of a...
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| Publicado en: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777844/ https://ncbi.nlm.nih.gov/pubmed/26733195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.699884 |
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