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Glu-311 in External Loop 4 of the Sodium/Proline Transporter PutP Is Crucial for External Gate Closure

The available structural information on LeuT and structurally related transporters suggests that external loop 4 (eL4) and the outer end of transmembrane domain (TM) 10′ participate in the reversible occlusion of the outer pathway to the solute binding sites. Here, the functional significance of eL4...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Bracher, Susanne, Guérin, Kamila, Polyhach, Yevhen, Jeschke, Gunnar, Dittmer, Sophie, Frey, Sabine, Böhm, Maret, Jung, Heinrich
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777837/
https://ncbi.nlm.nih.gov/pubmed/26728461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675306
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