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Core Transmembrane Domain 6 Plays a Pivotal Role in the Transport Cycle of the Sodium/Proline Symporter PutP

Crystal structures of transporters with a LeuT-type structural fold assign core transmembrane domain 6 (TM6′) a central role in substrate binding and translocation. Here, the function of TM6′ in the sodium/proline symporter PutP, a member of the solute/sodium symporter family, was investigated. A co...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bracher, Susanne, Schmidt, Claudia C., Dittmer, Sophie I., Jung, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207087/
https://ncbi.nlm.nih.gov/pubmed/27793991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753103
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