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Glu-311 in External Loop 4 of the Sodium/Proline Transporter PutP Is Crucial for External Gate Closure

The available structural information on LeuT and structurally related transporters suggests that external loop 4 (eL4) and the outer end of transmembrane domain (TM) 10′ participate in the reversible occlusion of the outer pathway to the solute binding sites. Here, the functional significance of eL4...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Bracher, Susanne, Guérin, Kamila, Polyhach, Yevhen, Jeschke, Gunnar, Dittmer, Sophie, Frey, Sabine, Böhm, Maret, Jung, Heinrich
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777837/
https://ncbi.nlm.nih.gov/pubmed/26728461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675306
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