Glu-311 in External Loop 4 of the Sodium/Proline Transporter PutP Is Crucial for External Gate Closure

The available structural information on LeuT and structurally related transporters suggests that external loop 4 (eL4) and the outer end of transmembrane domain (TM) 10′ participate in the reversible occlusion of the outer pathway to the solute binding sites. Here, the functional significance of eL4...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Bracher, Susanne, Guérin, Kamila, Polyhach, Yevhen, Jeschke, Gunnar, Dittmer, Sophie, Frey, Sabine, Böhm, Maret, Jung, Heinrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Membrane Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777837/
https://ncbi.nlm.nih.gov/pubmed/26728461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675306
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