IGF-1 Prevents Diastolic and Systolic Dysfunction Associated with Cardiomyopathy and Preserves Adrenergic Sensitivity

AIMS: Insulin-like growth factor 1 (IGF-1)-dependent signaling promotes exercise-induced physiological cardiac hypertrophy. However, the in vivo therapeutic potential of IGF-1 for heart disease is not well established. Here we test the potential therapeutic benefits of IGF-1 on cardiac function usin...

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Detalhes bibliográficos
Publicado no:Acta Physiol (Oxf)
Main Authors: Roof, Steve R., Boslett, James, Russell, Duncan, del Rio, Carlos, Alecusan, Joe, Zweier, Jay L., Ziolo, Mark T., Hamlin, Robert, Mohler, Peter J., Curran, Jerry
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777672/
https://ncbi.nlm.nih.gov/pubmed/26399932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12607
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