Impaired mitochondrial function is abrogated by dexrazoxane in doxorubicin-treated childhood acute lymphoblastic leukemia survivors

BACKGROUND: Impaired cardiac function in doxorubicin-treated childhood cancer survivors is partly mediated by disruption of mitochondrial energy production. Doxorubicin intercalates into mitochondrial DNA (mtDNA) disrupting genes encoding for polypeptides that make ATP. METHODS: This cross-sectional...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Lipshultz, Steven E., Anderson, Lynn M., Miller, Tracie L., Gerschenson, Mariana, Stevenson, Kristen E., Neuberg, Donna S., Franco, Vivian I., LiButti, Daniel E., Silverman, Lewis B., Vrooman, Lynda M., Sallan, Stephen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777628/
https://ncbi.nlm.nih.gov/pubmed/26762648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.29872
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados