Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial

BACKGROUND: Doxorubicin chemotherapy is associated with cardiomyopathy. Dexrazoxane reduces cardiac damage during treatment with doxorubicin in children with acute lymphoblastic leukaemia (ALL). We aimed to establish the long-term effect of dexrazoxane on the subclinical state of cardiac health in s...

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Detalhes bibliográficos
Main Authors: Lipshultz, Steven E, Scully, Rebecca E, Lipsitz, Stuart R, Sallan, Stephen E, Silverman, Lewis B, Miller, Tracie L, Barry, Elly V, Asselin, Barbara L, Athale, Uma, Clavell, Luis A, Larsen, Eric, Moghrabi, Albert, Samson, Yvan, Michon, Bruno, Schorin, Marshall A, Cohen, Harvey J, Neuberg, Donna S, Orav, E John, Colan, Steven D
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756093/
https://ncbi.nlm.nih.gov/pubmed/20850381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(10)70204-7
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