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Structure-Based Statistical Mechanical Model Accounts for the Causality and Energetics of Allosteric Communication

Allostery is one of the pervasive mechanisms through which proteins in living systems carry out enzymatic activity, cell signaling, and metabolism control. Effective modeling of the protein function regulation requires a synthesis of the thermodynamic and structural views of allostery. We present he...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Guarnera, Enrico, Berezovsky, Igor N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777440/
https://ncbi.nlm.nih.gov/pubmed/26939022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004678
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