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Antigen clasping by two antigen-binding sites of an exceptionally specific antibody for histone methylation
Antibodies have a well-established modular architecture wherein the antigen-binding site residing in the antigen-binding fragment (Fab or Fv) is an autonomous and complete unit for antigen recognition. Here, we describe antibodies departing from this paradigm. We developed recombinant antibodies to...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4776465/ https://ncbi.nlm.nih.gov/pubmed/26862167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522691113 |
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