Broad ranges of affinity and specificity of anti-histone antibodies revealed by a quantitative peptide immunoprecipitation assay

Antibodies directed against histone posttranslational modifications (PTMs) are critical tools in epigenetics research, particularly in the widely used chromatin immunoprecipitation (ChIP) experiments. However, a lack of quantitative methods for characterizing such antibodies has been a major bottlen...

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Detaylı Bibliyografya
Asıl Yazarlar: Nishikori, Shingo, Hattori, Takamitsu, Fuchs, Stephen M, Yasui, Norihisa, Wojcik, John, Koide, Akiko, Strahl, Brian D, Koide, Shohei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502729/
https://ncbi.nlm.nih.gov/pubmed/23041298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.09.022
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