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Discovery of Structurally Diverse Small-Molecule Compounds with Broad Antiviral Activity against Enteroviruses

Antiviral drugs do not currently exist for the treatment of enterovirus infections, which are often severe and potentially life-threatening. We conducted high-throughput molecular screening and identified a structurally diverse set of compounds that inhibit the replication of coxsackievirus B3, a co...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Zuo, Jun, Kye, Steve, Quinn, Kevin K., Cooper, Paige, Damoiseaux, Robert, Krogstad, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775951/
https://ncbi.nlm.nih.gov/pubmed/26711750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02646-15
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