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FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity

Early development is governed by the ability of pluripotent cells to retain the full range of developmental potential and respond accurately to developmental cues. This property is achieved in large part by the temporal and contextual regulation of gene expression by enhancers. Here, we evaluated re...

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Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Krishnakumar, Raga, Chen, Amy F., Pantovich, Marisol G., Danial, Muhammad, Parchem, Ronald J., Labosky, Patricia A., Blelloch, Robert
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775235/
https://ncbi.nlm.nih.gov/pubmed/26748757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.10.003
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