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MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells

Individual microRNAs (miRNAs) can target hundreds of messenger RNAs forming networks of presumably cooperating genes. To test this presumption, we functionally screened miRNAs and their targets in the context of de-differentiation of mouse fibroblasts to induced pluripotent stem cells (iPSCs). Along...

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Detalhes bibliográficos
Main Authors: Judson, Robert L, Greve, Tobias S, Parchem, Ronald J, Blelloch, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955211/
https://ncbi.nlm.nih.gov/pubmed/24037508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2665
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