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FOXD3 Regulates Pluripotent Stem Cell Potential by Simultaneously Initiating and Repressing Enhancer Activity

Early development is governed by the ability of pluripotent cells to retain the full range of developmental potential and respond accurately to developmental cues. This property is achieved in large part by the temporal and contextual regulation of gene expression by enhancers. Here, we evaluated re...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Krishnakumar, Raga, Chen, Amy F., Pantovich, Marisol G., Danial, Muhammad, Parchem, Ronald J., Labosky, Patricia A., Blelloch, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775235/
https://ncbi.nlm.nih.gov/pubmed/26748757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.10.003
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