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Novel Gefitinib Formulation with Improved Oral Bioavailability in Treatment of A431 Skin Carcinoma

PURPOSE: Oral administration of anticancer agents presents a series of advantages for patients. However, most of the anti-cancer drugs have poor water solubility leading to low bioavailability. METHODS: Controlled released spray dried matrix system of Gefitinib with hydroxypropyl β-cyclodextrin, chi...

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Vydáno v:Pharm Res
Hlavní autoři: Godugu, Chandraiah, Doddapaneni, Ravi, Patel, Apurva R, Singh, Rakesh, Mercer, Roger, Singh, Mandip
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774891/
https://ncbi.nlm.nih.gov/pubmed/26286185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1771-6
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