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Novel Gefitinib Formulation with Improved Oral Bioavailability in Treatment of A431 Skin Carcinoma
PURPOSE: Oral administration of anticancer agents presents a series of advantages for patients. However, most of the anti-cancer drugs have poor water solubility leading to low bioavailability. METHODS: Controlled released spray dried matrix system of Gefitinib with hydroxypropyl β-cyclodextrin, chi...
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| Publié dans: | Pharm Res |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4774891/ https://ncbi.nlm.nih.gov/pubmed/26286185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-015-1771-6 |
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