Blockade of CCR2 reduces macrophage influx and development of chronic renal damage in murine renovascular hypertension

Renovascular hypertension (RVH) is a common cause of both cardiovascular and renal morbidity and mortality. In renal artery stenosis (RAS), atrophy in the stenotic kidney is associated with an influx of macrophages and other mononuclear cells. We tested the hypothesis that chemokine receptor 2 (CCR2...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Kashyap, Sonu, Warner, Gina M., Hartono, Stella P., Boyilla, Rajendra, Knudsen, Bruce E., Zubair, Adeel S., Lien, Karen, Nath, Karl A., Textor, Stephen C., Lerman, Lilach O., Grande, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773828/
https://ncbi.nlm.nih.gov/pubmed/26661648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00131.2015
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