Blockade of CCR2 reduces macrophage influx and development of chronic renal damage in murine renovascular hypertension

Renovascular hypertension (RVH) is a common cause of both cardiovascular and renal morbidity and mortality. In renal artery stenosis (RAS), atrophy in the stenotic kidney is associated with an influx of macrophages and other mononuclear cells. We tested the hypothesis that chemokine receptor 2 (CCR2...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Kashyap, Sonu, Warner, Gina M., Hartono, Stella P., Boyilla, Rajendra, Knudsen, Bruce E., Zubair, Adeel S., Lien, Karen, Nath, Karl A., Textor, Stephen C., Lerman, Lilach O., Grande, Joseph P.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773828/
https://ncbi.nlm.nih.gov/pubmed/26661648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00131.2015
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