N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin

Neprilysin (NEP) and endothelin converting enzyme-1 (ECE-1) are two enzymes that degrade amyloid beta in the brain. Currently there are no molecules to stimulate the activity of these enzymes. Here we report, the discovery and characterisation of a peptide referred to as K49-P1-20, from the venom of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Smith, A. Ian, Rajapakse, Niwanthi W., Kleifeld, Oded, Lomonte, Bruno, Sikanyika, Nkumbu L., Spicer, Alexander J., Hodgson, Wayne C., Conroy, Paul J., Small, David H., Kaye, David M., Parkington, Helena C., Whisstock, James C., Kuruppu, Sanjaya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773759/
https://ncbi.nlm.nih.gov/pubmed/26931059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22413
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados