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A Lys49-PLA(2) myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling
Lys49-PLA(2) myotoxins, an important component of various viperid snake venoms, are a class of PLA(2)-homolog proteins deprived of catalytic activity. Similar to enzymatically active PLA(2) (Asp49) and to other classes of myotoxins, they cause severe myonecrosis. Moreover, these toxins are used as t...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406575/ https://ncbi.nlm.nih.gov/pubmed/22764102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.68 |
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