Inhibitors of Streptococcus pneumoniae Surface Endonuclease EndA Discovered by High-Throughput Screening Using a PicoGreen Fluorescence Assay

The human commensal pathogen, Streptococcus pneumoniae, expresses a number of virulence factors that promote serious pneumococcal diseases, resulting in significant morbidity and mortality worldwide. These virulence factors may give S. pneumoniae the capacity to escape immune defenses, resist antimi...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Biomol Screen
Huvudupphovsmän: Peterson, Eliza J.R., Kireev, Dmitri, Moon, Andrea F., Midon, Marika, Janzen, William P., Pingoud, Alfred, Pedersen, Lars C., Singleton, Scott F.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773034/
https://ncbi.nlm.nih.gov/pubmed/23015019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112461153
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk