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High-Throughput Screening for RecA Inhibitors Using a Transcreener Adenosine 5′-O-Diphosphate Assay

The activities of the bacterial RecA protein are involved in the de novo development and transmission of antibiotic resistance genes, thus allowing bacteria to overcome the metabolic stress induced by antibacterial agents. RecA is ubiquitous and highly conserved among bacteria, but has only distant...

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Библиографические подробности
Главные авторы: Peterson, Eliza J.R., Janzen, William P., Kireev, Dmitri, Singleton, Scott F.
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374383/
https://ncbi.nlm.nih.gov/pubmed/22192312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2011.0409
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