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Development of a high-throughput screening assay to identify inhibitors of the lipid kinase PIP5K1C

Phosphatidylinositol 4-phosphate 5-kinases (PIP5Ks) regulate a variety of cellular processes including signaling through G protein-coupled receptors (GPCRs), endocytosis, exocytosis, and cell migration. These lipid kinases synthesize phosphatidylinositol 4,5-bisphosphate (PIP(2)) from phosphatidylin...

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Detalhes bibliográficos
Publicado no:J Biomol Screen
Main Authors: Wright, Brittany D., Simpson, Catherine, Stashko, Michael, Kireev, Dmitri, Hull-Ryde, Emily A., Zylka, Mark J., Janzen, William P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610143/
https://ncbi.nlm.nih.gov/pubmed/25534829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057114564057
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