Inhibitors of Streptococcus pneumoniae Surface Endonuclease EndA Discovered by High-Throughput Screening Using a PicoGreen Fluorescence Assay

The human commensal pathogen, Streptococcus pneumoniae, expresses a number of virulence factors that promote serious pneumococcal diseases, resulting in significant morbidity and mortality worldwide. These virulence factors may give S. pneumoniae the capacity to escape immune defenses, resist antimi...

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Detalhes bibliográficos
Publicado no:J Biomol Screen
Main Authors: Peterson, Eliza J.R., Kireev, Dmitri, Moon, Andrea F., Midon, Marika, Janzen, William P., Pingoud, Alfred, Pedersen, Lars C., Singleton, Scott F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773034/
https://ncbi.nlm.nih.gov/pubmed/23015019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057112461153
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