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THE ANTI-INFLAMMATORY GLYCOPROTEIN, CD200, RESTORES NEUROGENESIS AND ENHANCES AMYLOID PHAGOCYTOSIS IN A MOUSE MODEL OF ALZHEIMER’S DISEASE
Cluster of Differentiation-200 (CD200) is an anti-inflammatory glycoprotein expressed in neurons, T cells, and B cells, and its receptor is expressed on glia. Both Alzheimer’s disease (AD) patients and mouse models display age-related or amyloid-β peptide (Aβ)-induced reductions in CD200. The goal o...
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| Udgivet i: | Neurobiol Aging |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4772879/ https://ncbi.nlm.nih.gov/pubmed/26315370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.07.027 |
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