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THE ANTI-INFLAMMATORY GLYCOPROTEIN, CD200, RESTORES NEUROGENESIS AND ENHANCES AMYLOID PHAGOCYTOSIS IN A MOUSE MODEL OF ALZHEIMER’S DISEASE

Cluster of Differentiation-200 (CD200) is an anti-inflammatory glycoprotein expressed in neurons, T cells, and B cells, and its receptor is expressed on glia. Both Alzheimer’s disease (AD) patients and mouse models display age-related or amyloid-β peptide (Aβ)-induced reductions in CD200. The goal o...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Varnum, Megan M., Kiyota, Tomomi, Ingraham, Kaitlin L, Ikezu, Seiko, Ikezu, Tsuneya
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772879/
https://ncbi.nlm.nih.gov/pubmed/26315370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.07.027
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