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c-Cbl, a Ubiquitin E3 Ligase That Targets Active β-Catenin: A NOVEL LAYER OF Wnt SIGNALING REGULATION

Regulation of transcriptionally active nuclear β-catenin during the Wnt-on phase is crucial to ensure controlled induction of Wnt target genes. Several ubiquitin E3 ligases are known to regulate cytosolic β-catenin during the Wnt-off phase, but little is known about the fate of active nuclear β-cate...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Chitalia, Vipul, Shivanna, Sowmya, Martorell, Jordi, Meyer, Rosana, Edelman, Elazer, Rahimi, Nader
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772756/
https://ncbi.nlm.nih.gov/pubmed/23744067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473801
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