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Optimized Near-IR fluorescent agents for in vivo imaging of Btk expression
Bruton’s tyrosine kinase (Btk) is intricately involved in anti-apototic signaling pathways in cancer and in regulating innate immune response. A number of Btk inhibitors are in development for use in treating B-cell malignancies and certain immunologic diseases. To develop robust companion imaging d...
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| Pubblicato in: | Bioconjug Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4772718/ https://ncbi.nlm.nih.gov/pubmed/26017814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00152 |
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