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Fluorescent vinblastine probes for live cell imaging

Herein we describe the synthesis of several fluorescent analogues of the clinically approved microtubule destabilizing agent vinblastine. The evaluated probes are the most potent described and provides the first example of uptake, distribution and live cell imaging using this well known antimitotic...

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Publicado en:Chem Commun (Camb)
Autores principales: Meimetis, Labros G., Giedt, Randy J., Mikula, Hannes, Carlson, Jonathan C., Kohler, Rainer H., Pirovich, David B., Weissleder, Ralph
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970878/
https://ncbi.nlm.nih.gov/pubmed/27439765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc04129a
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