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Fluorescent vinblastine probes for live cell imaging

Herein we describe the synthesis of several fluorescent analogues of the clinically approved microtubule destabilizing agent vinblastine. The evaluated probes are the most potent described and provides the first example of uptake, distribution and live cell imaging using this well known antimitotic...

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Détails bibliographiques
Publié dans:Chem Commun (Camb)
Auteurs principaux: Meimetis, Labros G., Giedt, Randy J., Mikula, Hannes, Carlson, Jonathan C., Kohler, Rainer H., Pirovich, David B., Weissleder, Ralph
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970878/
https://ncbi.nlm.nih.gov/pubmed/27439765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc04129a
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