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Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging()

We have developed a series of new ultrafluorogenic probes in the blue-green spectrum that display fluorescence enhancement exceeding 11,000-fold. These fluorogenic dyes integrate a coumarin fluorochrome with the bioorthogonal tetrazine-transcyclooctene (TCO) chemistry platform. By exploiting highly...

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Detalhes bibliográficos
Main Authors: Meimetis, Labros G., Carlson, Jonathan C.T., Giedt, Randy J., Kohler, Rainer H., Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122131/
https://ncbi.nlm.nih.gov/pubmed/24915832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201403890
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