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Single cell resolution in vivo imaging of DNA damage following PARP inhibition

Targeting DNA repair pathways is a powerful strategy to treat cancers. To gauge efficacy in vivo, typical response markers include late stage effects such as tumor shrinkage, progression free survival, or invasive repeat biopsies. These approaches are often difficult to answer critical questions suc...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Yang, Katherine S., Kohler, Rainer H., Landon, Matthieu, Giedt, Randy, Weissleder, Ralph
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434991/
https://ncbi.nlm.nih.gov/pubmed/25984718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10129
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