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Exchange Protein Directly Activated by cAMP Modulates Regulatory T-Cell-Mediated Immunosuppression
The cyclic adenosine monophosphate (cAMP) signaling pathway plays an essential role in immune functions. In this study we examined the role of the cAMP/EPAC1 (exchange protein directly activated by cAMP) axis in regulatory T-cell (Treg)-mediated immune suppression using genetic and pharmacologic app...
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| Pubblicato in: | Biochem J |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4772664/ https://ncbi.nlm.nih.gov/pubmed/25339598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140952 |
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