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Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling
Activated G(q) protein–coupled receptors (G(q)PCRs) can be desensitized by phosphorylation and β-arrestin binding. The kinetics and individual contributions of these two mechanisms to receptor desensitization have not been fully distinguished. Here, we describe the shut off of protease-activated rec...
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| Опубликовано в: : | J Gen Physiol |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4772372/ https://ncbi.nlm.nih.gov/pubmed/26927499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511477 |
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