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Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling
Activated G(q) protein–coupled receptors (G(q)PCRs) can be desensitized by phosphorylation and β-arrestin binding. The kinetics and individual contributions of these two mechanisms to receptor desensitization have not been fully distinguished. Here, we describe the shut off of protease-activated rec...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4772372/ https://ncbi.nlm.nih.gov/pubmed/26927499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511477 |
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