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β-arrestin–dependent PI(4,5)P(2) synthesis boosts GPCR endocytosis
β-arrestins regulate many cellular functions including intracellular signaling and desensitization of G protein–coupled receptors (GPCRs). Previous studies show that β-arrestin signaling and receptor endocytosis are modulated by the plasma membrane phosphoinositide lipid phosphatidylinositol-(4, 5)-...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092559/ https://ncbi.nlm.nih.gov/pubmed/33879605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011023118 |
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