Llwytho...

Contributions of protein kinases and β-arrestin to termination of protease-activated receptor 2 signaling

Activated G(q) protein–coupled receptors (G(q)PCRs) can be desensitized by phosphorylation and β-arrestin binding. The kinetics and individual contributions of these two mechanisms to receptor desensitization have not been fully distinguished. Here, we describe the shut off of protease-activated rec...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gen Physiol
Prif Awduron: Jung, Seung-Ryoung, Seo, Jong Bae, Deng, Yi, Asbury, Charles L., Hille, Bertil, Koh, Duk-Su
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772372/
https://ncbi.nlm.nih.gov/pubmed/26927499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511477
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