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Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells

Notch signaling can promote tumorigenesis in the nervous system and plays important roles in stem-like cancer cells. However, little is known about how Notch inhibition might alter tumor metabolism, particularly in lesions arising in the brain. The gamma-secretase inhibitor MRK003 was used to treat...

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Bibliografski detalji
Izdano u:Int J Cancer
Glavni autori: Kahlert, Ulf D., Cheng, Menglin, Koch, Katharina, Marchionni, Luigi, Fan, Xing, Raabe, Eric H., Maciaczyk, Jarek, Glunde, Kristine, Eberhart, Charles G.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772139/
https://ncbi.nlm.nih.gov/pubmed/26422827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29873
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